The easiest way to convert microfiche to PC is to have a scanning service bureau digitize it. Many people don't realize how inexpensive the service is. But beware: not all scanning service companies have the same pricing. In fact, some scanning companies are totally outside of the market range.
Generation Imaging, located in South Florida, can convert microfiche for you at wholesale prices. That means the microfiche scanning cost includes no reselling fees or markups. Generation Imaging has excellent high volume conversion prices, and will also gladly assist researchers, veterans, or clients with just one fiche card or a few of them.
There are a few other options you can choose to convert microfiche to digital images, but they are more time consuming and the quality is suspect. For example, if one believes a Yahoo Answers exchange you could take photos of microfiche frames with a camera instead of using a professional scanner. On another forum, someone suggested using a slide scanner or flatbed scanner. Based on internet advertisements, one may believe one can use a ScanPro 2000 to convert microfiche, but the quality levels and time it takes to scan one card doesn't justify the pricetag.
Speaking of pricetags, new high end microfiche equipment is in the $50,000+ range. You can invest time in looking for used equipment to convert microfiche, but speaking as someone who has been in this industry for decades, have fun training a labor force, creating a workflow, setting up a network, getting support, and replacing parts in a timely manner.